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MCM7 antibody (AA 360-719)
MCM7
Reactivity: Human
WB, IF, IP
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MCM7 Antibody
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Target
See all MCM7 Antibodies
MCM7
(Minichromosome Maintenance Complex Component 7 (MCM7))
Binding Specificity
All epitopes for MCM7 antibodies
AA 360-719
Reactivity
All reactivities for MCM7 antibodies
Human
Host
All hosts for MCM7 antibodies
Rabbit
Clonality
All clonalities for MCM7 antibodies
Polyclonal
Conjugate
All conjugates for MCM7 antibodies
This MCM7 antibody is un-conjugated
Application
All applications for MCM7 antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
Sequence
GGVDQSPRGM KIRGNINICL MGDPGVAKSQ LLSYIDRLAP RSQYTTGRGS SGVGLTAAVL RDSVSGELTL EGGALVLADQ GVCCIDEFDK MAEADRTAIH EVMEQQTISI AKAGILTTLN ARCSILAAAN PAYGRYNPRR SLEQNIQLPA ALLSRFDLLW LIQDRPDRDN DLRLAQHITY VHQHSRQPPS QFEPLDMKLM RRYIAMCREK QPMVPESLAD YITAAYVEMR REAWASKDAT YTSARTLLAI LRLSTALARL RMVDVVEKED VNEAIRLMEM SKDSLLGDKG QTARTQRPAD VIFATVRELV SGGRSVRFSE AEQRCVSRGF TPAQFQAALD EYEELNVWQV NASRTRITFV
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 360-719 of human MCM7 (NP_005907.3).
Isotype
IgG
Top Product
Discover our top product MCM7 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for MCM7
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Target
MCM7
(Minichromosome Maintenance Complex Component 7 (MCM7))
Alternative Name
MCM7 (MCM7 Products )
Synonyms
CDC47 antibody, MCM2 antibody, P1.1-MCM3 antibody, P1CDC47 antibody, P85MCM antibody, PNAS146 antibody, MCM7 antibody, AI747533 antibody, Mcmd7 antibody, mCDC47 antibody, chunp6911 antibody, nyz175 antibody, sr:nyz175 antibody, cdc47 antibody, cdc47-2 antibody, mcm7 antibody, xmcm7 antibody, CG4978 antibody, DmMCM7 antibody, DmeMCM7 antibody, Dmel\\CG4978 antibody, McM7 antibody, Mcp-PCR1 antibody, PCR1 antibody, anon-EST:Liang-1.66 antibody, clone 1.66 antibody, minichromosome maintenance complex component 7 antibody, mini-chromosome maintenance complex protein 7 antibody, minichromosome maintenance complex component 2 antibody, minichromosome maintenance complex component 7 L homeolog antibody, Minichromosome maintenance 7 antibody, minichromosome maintenance complex component 7 S homeolog antibody, MCM complex subunit Mcm7 antibody, MCM7 antibody, CDC47 antibody, Mcm7 antibody, MCM2 antibody, mcm7 antibody, mcm7.L antibody, mcm7.S antibody
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.,MCM7,CDC47,MCM2,P1.1-MCM3,P1CDC47,P85MCM,PNAS146,PPP1R104,Epigenetics & Nuclear Signaling,MCM7
Molecular Weight
44 kDa/60 kDa/81 kDa
Gene ID
4176
UniProt
P33993
Pathways
DNA Damage Repair , Mitotic G1-G1/S Phases , DNA Replication , Chromatin Binding , Synthesis of DNA
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