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Osteoprotegerin antibody (AA 22-280)
TNFRSF11B
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Osteoprotegerin Antibody
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Target
See all Osteoprotegerin (TNFRSF11B) Antibodies
Osteoprotegerin (TNFRSF11B)
(Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
Binding Specificity
All epitopes for Osteoprotegerin antibodies
AA 22-280
Reactivity
All reactivities for Osteoprotegerin antibodies
Human
Host
All hosts for Osteoprotegerin antibodies
Rabbit
Clonality
All clonalities for Osteoprotegerin antibodies
Polyclonal
Conjugate
All conjugates for Osteoprotegerin antibodies
This Osteoprotegerin antibody is un-conjugated
Application
All applications for Osteoprotegerin antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
ETFPPKYLHY DEETSHQLLC DKCPPGTYLK QHCTAKWKTV CAPCPDHYYT DSWHTSDECL YCSPVCKELQ YVKQECNRTH NRVCECKEGR YLEIEFCLKH RSCPPGFGVV QAGTPERNTV CKRCPDGFFS NETSSKAPCR KHTNCSVFGL LLTQKGNATH DNICSGNSES TQKCGIDVTL CEEAFFRFAV PTKFTPNWLS VLVDNLPGTK VNAESVERIK RQHSSQEQTF QLLKLWKHQN KDQDIVKKII QDIDLCENS
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-280 of human TNFRSF11B (NP_002537.3).
Isotype
IgG
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Osteoprotegerin
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Target
Osteoprotegerin (TNFRSF11B)
(Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
Alternative Name
TNFRSF11B (TNFRSF11B Products )
Synonyms
CD254 antibody, ODF antibody, OPGL antibody, OPTB2 antibody, RANKL antibody, TRANCE antibody, hRANKL2 antibody, sOdf antibody, OCIF antibody, OPG antibody, TR1 antibody, Opg antibody, ocif antibody, opg antibody, tr1 antibody, TNF superfamily member 11 antibody, TNF receptor superfamily member 11b antibody, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) antibody, TNF receptor superfamily member 11B antibody, tumor necrosis factor receptor superfamily member 11b S homeolog antibody, tumor necrosis factor receptor superfamily, member 11b antibody, TNFSF11 antibody, TNFRSF11B antibody, Tnfrsf11b antibody, tnfrsf11b.S antibody
Target Type
Chemical
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.,TNFRSF11B,OCIF,OPG,PDB5,TR1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Extracellular Matrix,Bone,Immunology & Inflammation,Cytokines,NF-kB Signaling Pathway,TNFRSF11B
Molecular Weight
46 kDa
Gene ID
4982
UniProt
O00300
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