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CYP2E1 antibody (AA 234-493)

CYP2E1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3023078
  • Target See all CYP2E1 Antibodies
    CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
    Binding Specificity
    • 15
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 234-493
    Reactivity
    • 71
    • 51
    • 37
    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Human
    Host
    • 78
    • 7
    • 3
    Rabbit
    Clonality
    • 75
    • 13
    Polyclonal
    Conjugate
    • 45
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP2E1 antibody is un-conjugated
    Application
    • 65
    • 27
    • 19
    • 14
    • 13
    • 9
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KVIKNVAEVK EYVSERVKEH HQSLDPNCPR DLTDCLLVEM EKEKHSAERL YTMDGITVTV ADLFFAGTET TSTTLRYGLL ILMKYPEIEE KLHEEIDRVI GPSRIPAIKD RQEMPYMDAV VHEIQRFITL VPSNLPHEAT RDTIFRGYLI PKGTVVVPTL DSVLYDNQEF PDPEKFKPEH FLNENGKFKY SDYFKPFSTG KRVCAGEGLA RMELFLLLCA ILQHFNLKPL VDPKDIDLSP IHIGFGCIPP RYKLCVIPRS
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 234-493 of human CYP2E1 (NP_000764.1).
    Isotype
    IgG
    Top Product
    Discover our top product CYP2E1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Ma, Zhu, Tan, Mao, Tang, Shen, Zhang, Kuang, Fei, Yang, Wang: "Gpr110 deficiency decelerates carcinogen-induced hepatocarcinogenesis via activation of the IL-6/STAT3 pathway." in: American journal of cancer research, Vol. 7, Issue 3, pp. 433-447, (2017) (PubMed).

  • Target
    CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
    Alternative Name
    CYP2E1 (CYP2E1 Products)
    Synonyms
    CYP2E1 antibody, CYP2E antibody, CYPIIE1 antibody, CPE1 antibody, P450-J antibody, P450C2E antibody, Cyp2e antibody, cytochrome P450, family 2, subfamily E, polypeptide 1 antibody, cytochrome P450 2E1 antibody, cytochrome P450 2E1-like antibody, cytochrome P450 family 2 subfamily E member 1 antibody, cytochrome P450, family 2, subfamily e, polypeptide 1 antibody, CYP2E1 antibody, PTRG_07411 antibody, LOC100342572 antibody, LOC100727914 antibody, LOC101843716 antibody, Cyp2e1 antibody
    Background
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.,CYP2E1,CPE1,CYP2E,P450-J,P450C2E,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Lipid Metabolism,Cytochromes,Lipases,Drug metabolism,Cardiovascular,Lipids,CYP2E1
    Molecular Weight
    56 kDa
    Gene ID
    1571
    UniProt
    P05181
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