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CD2 antibody

CD2 Reactivity: Human FACS, IF, Func Host: Mouse Monoclonal 1E7E8-G4 unconjugated

Catalog No. ABIN3024308

Datasheet as PDF

Target See all CD2 Antibodies

CD2
Reactivity
157

30

17

16

12

10

10

6

5

3

3

3

3

3

2

2

2

1

1

1

1

1

1
Human
Host
127

44

18

2
Mouse
Compatible Secondaries
Clonality
145

44

2
Monoclonal
Conjugate
84

21

21

16

6

4

4

4

4

4

4

3

2

2

2

2

1

1

1

1

1

1

1

1
This CD2 antibody is un-conjugated
Application
136

51

51

34

31

31

21

12

11

10

2

2

1

1

1

1

1
Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Purification

Protein G affinity chromatography

Immunogen

Human Thymocytes/Sezary T cells were used as the immunogen for this CD2 antibody.

Clone

1E7E8-G4

Isotype

IgG2a kappa

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anti-CD2 (CD2) (AA 25-140) antibody
CD2 Reactivity: Mouse FACS, WB, ELISA, IHC, ICC Host: Mouse Monoclonal 3D1E3 unconjugated

anti-CD2 (CD2) (N-Term) antibody
CD2 Reactivity: Human WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-CD2 (CD2) antibody (FITC)
CD2 Reactivity: Human FACS Host: Mouse Monoclonal LT2 FITC

anti-CD2 (CD2) antibody (PE)
CD2 Reactivity: Human FACS Host: Mouse Monoclonal LT2 PE

anti-CD2 (CD2) (AA 1-351) antibody
CD2 Reactivity: Human WB, IHC (p) Host: Mouse Polyclonal unconjugated

anti-CD2 (CD2) antibody
CD2 Reactivity: Human FACS, IF, WB, Func Host: Mouse Monoclonal 1E7E8-G4 unconjugated

anti-CD2 (CD2) (AA 25-209) antibody
CD2 Reactivity: Human IF, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-CD2 (CD2) antibody
CD2 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-65 unconjugated

anti-CD2 (CD2) antibody
CD2 Reactivity: Human FACS, IP Host: Mouse Monoclonal LT2 unconjugated

Application Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.\. Functional Testing: order azide-free format,FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL

Restrictions

For Research Use only
Concentration

1 mg/mL

Buffer

1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative

Azide free

Storage

4 °C,-20 °C

Storage Comment

Store the CD2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Target

CD2

Alternative Name

CD2 (CD2 Products)

Synonyms

CD2 antibody, LFA-2 antibody, Ly-37 antibody, Ly37 antibody, SRBC antibody, T11 antibody, CD2R antibody, LFA2 antibody, OX-34 antibody, OX34 antibody, CD2 molecule antibody, CD2 antigen antibody, Cd2 molecule antibody, CD2 antibody, Cd2 antibody

Background

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Gene ID

914