FGF23 antibody

Catalog No. ABIN3024848

Product Details anti-FGF23 Antibody

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGF23 antibody is un-conjugated

Application: ELISA, Functional Studies (Func)

Purification: Protein G purified FGF-23 antibody

Immunogen: A recombinant human FGF-23 protein was used as the immunogen for this antibody.

Clone: FGF23-638

Isotype: IgG1 kappa

Application Details

Application Notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FGF-23 antibody to be titered up or down for optimal performance.\. ELISA: order BSA-free format for coating,Functional testing: order BSA/azide-free format

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the FGF-23 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for FGF23

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Alternative Name: FGF-23 (FGF23 Products)

Synonyms: FGF23 antibody, ADHR antibody, FGFN antibody, HPDR2 antibody, HYPF antibody, PHPTC antibody, fibroblast growth factor 23 antibody, fgf23 antibody, FGF23 antibody, Fgf23 antibody

Background: Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the family include the oncogenes FGF3 (Int2) and FGF4 (hst/Kaposi), FGF5, FGF6, FGF7 (KGF), FGF8 (AIGF), FGF9 (GAF) and FGF10 through FGF-23. Members of the family share 30-55 % amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

Gene ID: 8074

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion