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Survivin antibody
BIRC5
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Survivin Antibody
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Target
See all Survivin (BIRC5) Antibodies
Survivin (BIRC5)
(Baculoviral IAP Repeat-Containing 5 (BIRC5))
Reactivity
All reactivities for Survivin antibodies
Human
Host
All hosts for Survivin antibodies
Rabbit
Clonality
All clonalities for Survivin antibodies
Polyclonal
Conjugate
All conjugates for Survivin antibodies
This Survivin antibody is un-conjugated
Application
All applications for Survivin antibodies
Western Blotting (WB)
Purification
Protein A affinity chromatography
Immunogen
A recombinant protein fragment from human Survivin was used as the immunogen for this antibody.
Isotype
IgG
Top Product
Discover our top product BIRC5 Primary Antibody
Alternatives
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Application Details
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Application Notes
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.\. Western blot: 2-5 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target Details for Survivin
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Target
Survivin (BIRC5)
(Baculoviral IAP Repeat-Containing 5 (BIRC5))
Alternative Name
Survivin (BIRC5 Products )
Synonyms
AP14 antibody, API4 antibody, EPR-1 antibody, AAC-11 antibody, Api4 antibody, TIAP antibody, survivin40 antibody, bir5a antibody, survivin antibody, BIR1 antibody, Su2 antibody, XBIR1 antibody, XSurvivin1 antibody, Xsvv1 antibody, api4 antibody, bir1-A antibody, epr-1 antibody, svv1 antibody, xSurvivin antibody, xsurv antibody, Su1 antibody, birc5.2 antibody, svv2 antibody, xSurvivin2 antibody, bir5b antibody, SIX antibody, birc5.2-a antibody, birc5.2-b antibody, baculoviral IAP repeat containing 5 antibody, baculoviral IAP repeat-containing 5 antibody, baculoviral IAP repeat containing 5a antibody, baculoviral IAP repeat-containing 5, gene 1 L homeolog antibody, baculoviral IAP repeat containing 5 L homeolog antibody, baculoviral IAP repeat containing 5b antibody, baculoviral IAP repeat containing 5 S homeolog antibody, BIRC5 antibody, Birc5 antibody, birc5a antibody, birc5.1.L antibody, birc5.2.L antibody, birc5b antibody, birc5.2.S antibody
Background
Survivin, also called BIRC5, is a protein encoded by the human BIRC5 gene. It is a member of the IAP (inhibitor of apoptosis family. Survivin binds to the active form of Caspase-3 and -7, effector or executioner caspases, preventing them from continuing the apoptosis-signaling cascade. Expression is regulated by p53, a regulator of apoptosis-control genes which interacts with the Survivin gene promoter region to repress its expression at the mRNA and protein level.
Gene ID
332
Pathways
Apoptosis , Cell Division Cycle , Nuclear Hormone Receptor Binding
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