CD47 antibody

Catalog No. ABIN3026434

The Mouse Monoclonal anti-CD47 antibody (Clone IAP-964-B6H12-2) (ABIN3026434) specifically detects CD47 in FACS and IF. The antibody is reactive with Human samples.

Quick Overview for CD47 antibody (ABIN3026434)

Target: CD47

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD47 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: IAP-964-B6H12-2

Product Details anti-CD47 Antibody

Purpose: CD47 Antibody Cocktail

Characteristics: This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Purification: Protein G affinity chromatography

Immunogen: Recombinant human protein (IAP/964) and intact CD47 purified from placenta (B6H12.2) were used as the immunogen for the CD47 antibody cocktail.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the CD47 antibody cocktail should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CD47 antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD47

Target: CD47

Alternative Name: CD47

Background: This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

UniProt: Q08722