The stated application concentrations are suggested starting amounts. Titration of the ARA9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
-20 °C
Storage Comment
After reconstitution, the ARA9 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Target
AIP
(Aryl Hydrocarbon Receptor Interacting Protein (AIP))
Aryl hydrocarbon receptor-associated protein-9 (ARA9), also known as AIP or XAP-2, is a protein that in humans is encoded by the AIP gene. This gene is mapped to 11q13.2. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. ARA9/AIP may play a positive role in aryl hydrocarbon receptor-mediated signalling possibly by influencing its receptivity for ligand and/or its nuclear targeting. It has been shown that ARA9 is the cellular negative regulator of the hepatitis B virus (HBV) X protein. Mutations may be the cause of a familial form of acromegaly, familial isolated pituitary adenoma (FIPA).