CCL7 antibody (AA 24-97)

Catalog No. ABIN3030488

Product Details anti-CCL7 Antibody

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Binding Specificity: AA 24-97

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity

Immunogen: Mouse partial recombinant protein (AA 24-97) was used as the immunogen for this CCL7 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the CCL7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the CCL7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for CCL7

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Alternative Name: CCL7 (MCP3) (CCL7 Products)

Synonyms: CCL7 antibody, FIC antibody, MARC antibody, MCP-3 antibody, MCP3 antibody, NC28 antibody, SCYA6 antibody, SCYA7 antibody, Scya7 antibody, fic antibody, marc antibody, mcp3 antibody, C-C motif chemokine ligand 7 antibody, chemokine (C-C motif) ligand 7 antibody, CCL7 antibody, Ccl7 antibody

Background: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, the gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3/CCL7 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response.

Gene ID: 20306