PDGFB antibody (AA 82-190)

Catalog No. ABIN3032247

Product Details anti-PDGFB Antibody

Target: PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))

Binding Specificity: AA 82-190

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFB antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 82-190) was used as the immunogen for this PDGF-B antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the PDGF-B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the PDGF-B antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for PDGFB

Target: PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))

Alternative Name: PDGF-B (PDGFB Products)

Synonyms: PDGF-2 antibody, PDGF2 antibody, SIS antibody, SSV antibody, c-sis antibody, pdgf2 antibody, sis antibody, si:ch211-79m20.1 antibody, si:dkey-261d11.1 antibody, PDGF-B antibody, Sis antibody, platelet derived growth factor subunit B antibody, platelet-derived growth factor beta polypeptide antibody, platelet derived growth factor subunit B S homeolog antibody, platelet-derived growth factor beta polypeptide a antibody, platelet derived growth factor, B polypeptide antibody, PDGFB antibody, pdgfb.S antibody, pdgfba antibody, Pdgfb antibody

Background: Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene. The protein encoded by this gene is a member of the platelet-derived growth factor family. PDGF-B can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Growth factor plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. PDGF-B plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGF-A.

Gene ID: 5155

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling