SOX7 antibody (C-Term)

Catalog No. ABIN3032742

Product Details anti-SOX7 Antibody

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX7 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human SOX7 (LISVLADATATYYNSYSVS) was used as the immunogen for this SOX7 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the SOX7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the SOX7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for SOX7

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Alternative Name: SOX7 (SOX7 Products)

Synonyms: sox7-A antibody, xSox7 antibody, SRY-box 7 antibody, SRY (sex determining region Y)-box 7 antibody, SRY box 7 antibody, SRY-box 7 L homeolog antibody, SOX7 antibody, Sox7 antibody, sox7 antibody, sox7.L antibody

Background: SOX7 belongs to SOX gene family and member proteins are transcription factors with critical roles in the regulation of diverse developmental processes. In cotransfected 293 cells, SOX7 reduced < a href=../search_result.php?search_txt=wnt>Wnt/< a href=../search_result.php?search_txt=catenin>beta-catenin stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.

UniProt: Q9BT81

Pathways: Positive Regulation of Endopeptidase Activity