An amino acid sequence from the C-terminus of human SOX7 (LISVLADATATYYNSYSVS) was used as the immunogen for this SOX7 antibody (100% homologous in human, mouse and rat).
SOX7
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
The stated application concentrations are suggested starting amounts. Titration of the SOX7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
-20 °C
Storage Comment
After reconstitution, the SOX7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Target
SOX7
(SRY (Sex Determining Region Y)-Box 7 (SOX7))
SOX7 belongs to SOX gene family and member proteins are transcription factors with critical roles in the regulation of diverse developmental processes. In cotransfected 293 cells, SOX7 reduced < a href=../search_result.php?search_txt=wnt>Wnt/< a href=../search_result.php?search_txt=catenin>beta-catenin stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.