Glutamate Receptor 3 antibody (Middle Region)

Catalog No. ABIN3042581

Product Details anti-Glutamate Receptor 3 Antibody

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Binding Specificity: AA 394-412, Middle Region

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Glutamate receptor 3(GRIA3) detection. Tested with WB in Human,Mouse,Rat.

Sequence: RKAGYWNEYE RFVPFSDQQ

Cross-Reactivity (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Glutamate receptor 3(GRIA3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: glutamate receptor, ionotropic, AMPA 3
Protein Name: Glutamate receptor 3

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human GRIA3 (394-412aa RKAGYWNEYERFVPFSDQQ), identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Alternative Name: GRIA3 (GRIA3 Products)

Synonyms: AMPA antibody, gria3 antibody, GRIN3A antibody, glur3b antibody, gria3.2 antibody, zfGRIA3[b] antibody, si:bz1o18.1 antibody, SI:zC231H1.1 antibody, si:zc140k5.3 antibody, GLUR3 antibody, GLUR-C antibody, GLUR3/C antibody, GRIA3 antibody, glur3 antibody, GluA3 antibody, GluR-3 antibody, GluR-C antibody, GluR-K3 antibody, GLUR-K3 antibody, GLURC antibody, MRX94 antibody, 2900064I19Rik antibody, Glur-3 antibody, Glur3 antibody, Gluralpha3 antibody, glutamate receptor, ionotropic, AMPA 3b antibody, glutamate ionotropic receptor AMPA type subunit 3 antibody, glutamate receptor, ionotropic, AMPA 3 antibody, glutamate receptor, ionotropic, AMPA 3 L homeolog antibody, glutamate receptor, ionotropic, AMPA3 (alpha 3) antibody, gria3b antibody, GRIA3 antibody, gria3 antibody, gria3.L antibody, Gria3 antibody

Background: Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA) receptors. It is mapped to Xq25. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. In addition to that, GRIA3 has been shown to interact with GRIP1 and PICK1.

Synonyms: AMPA 3 antibody|AMPA selective glutamate receptor 3 antibody|AMPA-selective glutamate receptor 3 antibody|GluA3 antibody|GLUK3 antibody|GLUR 3 antibody|GLUR C antibody|GLUR K3 antibody|GluR-3 antibody|GluR-C antibody|GluR-K3 antibody|GLUR3 antibody|GLURC antibody|Glutamate receptor 3 antibody|Glutamate receptor C antibody|Glutamate Receptor Ionotrophic AMPA 3 antibody|Glutamate receptor ionotropic antibody|Glutamate receptor subunit 3 antibody|GRIA 3 antibody|Gria3 antibody|GRIA3_HUMAN antibody|GRM 3 antibody|Ionotrophic Glutamate Receptor antibody|Metabotropic glutamate receptor 3 precursor antibody|mGlu 3 antibody|MGLUR 3 antibody|MRX94 antibody

UniProt: P42263

Pathways: PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane