DDR2 antibody (C-Term)
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- Target See all DDR2 Antibodies
- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
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Binding Specificity
- AA 834-855, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DDR2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit IgG polyclonal antibody for Discoidin domain-containing receptor 2(DDR2) detection. Tested with WB in Human.
- Sequence
- RDTKNRPSFQ EIHLLLLQQG DE
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Discoidin domain-containing receptor 2(DDR2) detection. Tested with WB in Human.
Gene Name: discoidin domain receptor tyrosine kinase 2
Protein Name: Discoidin domain-containing receptor 2 - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human DDR2(834-855aa RDTKNRPSFQEIHLLLLQQGDE), different from the related mouse sequence by three amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product DDR2 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for DDR2 is approximately 5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Preservative
- Thimerosal (Merthiolate), Sodium azide
- Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Expiry Date
- 12 months
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- Target
- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
- Alternative Name
- DDR2 (DDR2 Products)
- Synonyms
- MIG20a antibody, NTRKR3 antibody, TKT antibody, TYRO10 antibody, AW495251 antibody, Ntrkr3 antibody, tyro10 antibody, DDR2 antibody, Tyro10 antibody, ddr2 antibody, si:ch211-193c2.1 antibody, discoidin domain receptor tyrosine kinase 2 antibody, discoidin domain receptor family, member 2 antibody, discoidin domain receptor family, member 2, like antibody, DDR2 antibody, Ddr2 antibody, ddr2l antibody
- Background
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DDR2(Discoidin domain receptor family, member 2) also known as NTRKR3 or TKT, is a human gene. Ddr2 protein was detected in most mouse tissues examined. Highest levels of phosphorylated Ddr2 were detected in lung, ovary, and skin, which did not correlate with Ddr2 protein levels. The DDR2 gene is mapped 1q23.3. Receptor tyrosine kinases(RTKs) play a key role in the communication of cells with their microenvironment.Using in situ hybridization with 1-week-old mice, Labrador et al.(2001) found that Ddr2 was expressed along chondrocyte columns in the proliferative region of the growth plate.Ddr2mRNA was also present, although dispersed, at areas of calcified cartilage in the cartilage-bone junction, as well as in the trabecular bone surface. Bargal et al.(2009) also identified a splice site mutation in the DDR2 gene, which resulted in the skipping of exon 17, in one of the Jewish families with SMED-SL originally reported by Borochowitz et al.(1993).
Synonyms: CD167 antigen-like family member B antibody|CD167b antibody|CD167b antigen antibody|Cell migration inducing protein 20 antibody|DDR 2 antibody|DDR2 antibody|DDR2_HUMAN antibody|Discoidin domain containing receptor 2 antibody|Discoidin domain receptor 2 antibody|Discoidin domain receptor family member 2 antibody|discoidin domain receptor tyrosine kinase 2 antibody|Discoidin domain-containing receptor 2 antibody|discoidin domain-containing receptor tyrosine kinase 2 antibody|Hydroxyaryl protein kinase antibody|MIG20a antibody|Migration inducing gene 16 protein antibody|Neurotrophic tyrosine kinase antibody|Neurotrophic tyrosine kinase receptor related 3 antibody|NTRKR 3 antibody|NTRKR3 antibody|Receptor protein tyrosine kinase TKT antibody|Receptor protein-tyrosine kinase TKT antibody|Receptor related 3 antibody|receptor-related 3 antibody|TKT antibody|TYRO 10 antibody|TYRO10 antibody|Tyrosine kinase receptor related to neurotrophic TRK antibody|Tyrosine protein kinase TYRO 10 antibody|Tyrosine protein kinase TYRO10 antibody|Tyrosine-protein kinase TYRO10 antibody|Tyrosylprotein kinase antibody - UniProt
- Q16832
- Pathways
- RTK Signaling
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