IL3RA antibody (Middle Region)

Catalog No. ABIN3043144

Product Details anti-IL3RA Antibody

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Binding Specificity: AA 135-151, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL3RA antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Interleukin-3 receptor subunit alpha(IL3RA) detection. Tested with WB in Human.

Sequence: QYDLYLNVAN RRQQYEC

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Interleukin-3 receptor subunit alpha(IL3RA) detection. Tested with WB in Human.
Gene Name: interleukin 3 receptor, alpha(low affinity)
Protein Name: Interleukin-3 receptor subunit alpha(IL-3 receptor subunit alpha/IL-3R subunit alpha/IL-3R-alpha/IL-3RA)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human IL3RA(135-151aa QYDLYLNVANRRQQYEC).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Alternative Name: IL3RA (IL3RA Products)

Synonyms: CD123 antibody, IL3R antibody, IL3RAY antibody, IL3RX antibody, IL3RY antibody, hIL-3Ra antibody, CDw123 antibody, SUT-1 antibody, Cyrl antibody, interleukin 3 receptor subunit alpha antibody, interleukin 3 receptor, alpha chain antibody, IL3RA antibody, Il3ra antibody

Background: IL3RA(INTERLEUKIN 3 RECEPTOR, ALPHA), also called CD123(Cluster of Differentiation 123), is a human gene. The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2(CSF2/GM-CSF), and interleukin 5(IL5). The IL3RA is mapped on Xp22.33. The genomic structures of IL3RA and CSF2RA are very similar and share an additional exon encoding part of the C-terminal domain not found in other members of this gene family. As in human hematopoietic cells, IL3 and GMCSF competed for binding in fibroblasts expressing the cDNAs for IL3RA, CSF2RA, and the common beta subunit, indicating that different alpha subunits compete for a common beta subunit.

Synonyms: CD123 antibody|CD123 antigen antibody|hIL 3Ra antibody|hIL-3Ra antibody|hIL3Ra antibody|IL 3 receptor alpha SP2 isoform antibody|IL 3R alpha antibody|IL-3 receptor subunit alpha antibody|IL-3R subunit alpha antibody|IL-3R-alpha antibody|IL-3RA antibody|IL3 Receptor alpha antibody|IL3R antibody|IL3Ra antibody|IL3RA_HUMAN antibody|IL3RAX antibody|IL3RAY antibody|IL3RX antibody|IL3RY antibody|Interleukin 3 receptor alpha chain antibody|Interleukin 3 receptor, alpha(low affinity) antibody|Interleukin 3 receptor, alpha antibody|Interleukin-3 Receptor alpha antibody|Interleukin-3 receptor subunit alpha antibody|Interleukin3 receptor antibody|Interleukin3 receptor, Y-chromosomal antibody

UniProt: P26951

Pathways: JAK-STAT Signaling