PIK3R2 antibody (Middle Region)

Catalog No. ABIN3043605

Product Details anti-PIK3R2 Antibody

Target: PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Binding Specificity: AA 427-463, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3R2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Phosphatidylinositol 3-kinase regulatory subunit beta(PIK3R2) detection. Tested with WB in Human.

Sequence: KYQQDQIVKE DSVEAVGAQL KVYHQQYQDK SREYDQL

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Phosphatidylinositol 3-kinase regulatory subunit beta(PIK3R2) detection. Tested with WB in Human.
Gene Name: phosphoinositide-3-kinase, regulatory subunit 2 (beta)
Protein Name: Phosphatidylinositol 3-kinase regulatory subunit beta

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human PIK3R2 (427-463aa KYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQL), different from the related mouse sequence by two amino acids, and from the related rat sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for PIK3R2

Target: PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Alternative Name: PIK3R2 (PI3K p85b Products)

Synonyms: MPPH antibody, P85B antibody, p85 antibody, p85-BETA antibody, pik3r2 antibody, MGC80449 antibody, p85beta antibody, phosphoinositide-3-kinase regulatory subunit 2 antibody, phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta) antibody, phosphoinositide-3-kinase, regulatory subunit 2 (beta) antibody, PIK3R2 antibody, pik3r2 antibody, Pik3r2 antibody

Background: PIK3R2 (Phosphatidylinositol 3-kinase, regulatory subunit 2), also called p85-Beta, is an enzyme that in humans is encoded by the PIK3R2 gene. The PIK3R2 gene is mapped on 19p13.11. Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene.

Synonyms: p85 antibody|p85 beta antibody|P85B antibody|P85B_HUMAN antibody|Phosphatidylinositol 3 kinase antibody|Phosphatidylinositol 3 kinase regulatory beta subunit antibody| Phosphatidylinositol 3 kinase regulatory subunit beta antibody|Phosphatidylinositol 3 kinase regulatory subunit polypeptide 2 antibody|Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 2 (p85 beta) antibody| Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta antibody|Phosphatidylinositol 3-kinase regulatory subunit beta antibody| Phosphoinositide 3 kinase regulatory subunit 2 (beta) antibody|Phosphoinositide 3 kinase regulatory subunit 2 antibody| Phosphoinositide 3 kinase regulatory subunit polypeptide 2 (p85 beta) antibody|Phosphoinositide 3 kinase regulatory subunit polypeptide 2 antibody| Phosphoinositide 3 kinase, regulatory subunit 2 (beta) antibody|Phosphoinositide 3 kinase, regulatory subunit 2 (p85 beta) antibody|PI3 kinase p85 beta subunit antibody|PI3 kinase p85 subunit beta antibody|PI3-kinase regulatory subunit beta antibody|PI3-kinase subunit p85-beta antibody|PI3K antibody|PI3K regulatory subunit beta antibody|PIK3R 2 antibody|PIK3R2 antibody| PtdIns 3 kinase p85 beta antibody|PtdIns-3-kinase regulatory subunit beta antibody|PtdIns-3-kinase regulatory subunit p85-beta antibody

Gene ID: 5296

UniProt: O00459

Pathways: VEGF Signaling, BCR Signaling