p21 antibody

Catalog No. ABIN306572

The Mouse Monoclonal anti-p21 antibody is suitable to detect p21 in samples from Human. It has been validated for WB, IHC and IP.

Quick Overview for p21 antibody (ABIN306572)

Target: p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This p21 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: DCS-60

Product Details anti-p21 Antibody

Purpose: Mouse anti Human p21 WAF-1

Characteristics: The p21waf1 tumor suppressor protein shows no cross reactivity with the closely related inhibitors .p21waf1 is a specific inhibitor of cdk79s, and is a tumor suppressor involved in the pathogenesis of a number of malignancies including colon and breast carcinoma

Purification: Protein A/G Chromatography

Isotype: IgG2a

Application Details

Application Notes: 1-5 μg /mL for Western Blot, Immunoflurescence, Immunoprecipitation (co-precipitates cdk4/cdk6)

Restrictions: For Research Use only

Handling

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for p21

Target: p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))

Alternative Name: p21 WAF-1

Background: P21waf1, hp21, Cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, Melanoma differentiation-associated protein 6

UniProt: P38936

Pathways: p53 Signaling, PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy