c-MYC antibody
Quick Overview for c-MYC antibody (ABIN306632)
Target
See all c-MYC (MYC) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Isotype
- IgG2a
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Restrictions
- For Research Use only
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- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
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Alternative Name
- c-myc
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Background
- Human c-myc belongs to a family of 5 myc oncogenes. Amplification of c-myc has been found in several tpes of human tumors including breast and colon carcinomas. Induction of c-myc in cells grown in the appropriate growth factors or co-expression with survival genes, such as bcl-2 causes cell proliferation. In the abscence of these factors, c-myc expression causes cell death. c-myc gene gives rise to at least two nuclear phosphoproteins of 64kDa and 67kDa. Synonyms: cmyc, Myc proto-oncogene protein, transcription factor p64.
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UniProt
- P01106
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Pathways
- p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
Target
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