PPAP2A antibody
-
- Target See all PPAP2A Antibodies
- PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PPAP2A antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Characteristics
- EC 3.1.3.4, Lipid Phosphate Phosphatase 1, Phosphatidic acid phosphatase 2a,Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. It catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG), and is a pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. It is a major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. It may control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. Its down-regulation may contribute to the development of colon adenocarcinoma.
- Immunogen
- Synthetic peptide derived from the LPP1 protein
- Isotype
- IgG
- Top Product
- Discover our top product PPAP2A Primary Antibody
-
-
- Application Notes
- Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
- Restrictions
- For Research Use only
-
- Buffer
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
-
- Target
- PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))
- Alternative Name
- Lysophospholipid Phosphatase (LPP) 1/1A (PPAP2A Products)
- Synonyms
- PPAP2A antibody, wun antibody, LLP1a antibody, LPP1 antibody, PAP-2a antibody, PAP2 antibody, Hic53 antibody, Hpic53 antibody, LPP-1 antibody, mPAP antibody, PAP2A antibody, PAP2a2 antibody, phospholipid phosphatase 1 antibody, phosphatidic acid phosphatase type 2A antibody, phospholipid phosphatase 1 L homeolog antibody, PLPP1 antibody, plpp1 antibody, Ppap2a antibody, plpp1.L antibody, Plpp1 antibody
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
-