GAS6 antibody

Catalog No. ABIN317613

Product Details anti-GAS6 Antibody

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAS6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of Gas6 protein.(region surrounding Gly309)

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: Western Blot: 1/500-1/1000. ELISA: 1/40000-1/60000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GAS6

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Alternative Name: GAS6 / AXLLG (GAS6 Products)

Synonyms: fj34a12 antibody, zgc:63860 antibody, wu:fj34a12 antibody, MGC68463 antibody, gas6 antibody, MGC83872 antibody, GAS6 antibody, Gas-6 antibody, AXLLG antibody, AXSF antibody, growth arrest specific 6 antibody, growth arrest-specific 6 antibody, growth arrest specific 6 L homeolog antibody, growth arrest specific 6 S homeolog antibody, GAS6 antibody, gas6 antibody, gas6.L antibody, gas6.S antibody, Gas6 antibody

Background: Growth arrest specific proteins, including Gas1 and Gas6, are activated in quiescent cells. Gas1-induced growth arrest is mediated by p53, and Gas1 appears to be able to suppress tumor cell growth. Gas6, a ligand for the tyrosine kinase receptor Axl, was initially identified as a member of the vitamin K-dependent protein family and exhibits a high degree of amino acid sequence homology to protein S, a negative co-regulator in the coagulation pathway.Synonyms: AXL receptor tyrosine kinase ligand, GAS-6, Growth arrest-specific protein 6

Gene ID: 2621

NCBI Accession: NP_000811

UniProt: Q14393

Pathways: RTK Signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response