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IRF7 antibody (Interferon Regulatory Factor 7) (C-Term) Primary Antibody

IRF7 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN318754
$580.80
Plus shipping costs $45.00
0.1 mg ABIN318754
0.1 mg ABIN318754
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Available
  • Target
    IRF7
    Binding Specificity
    • 16
    • 16
    • 15
    • 8
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 78
    • 54
    • 53
    • 17
    • 8
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 73
    • 5
    Rabbit
    Clonality
    • 65
    • 13
    Polyclonal
    Conjugate
    • 26
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This IRF7 antibody is un-conjugated
    Application
    • 39
    • 24
    • 17
    • 14
    • 13
    • 12
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    This antibody detects an epitope within the C-terminal of Human Interferon Regulatory Factor 7 (IRF7).
    Purification
    Affinity Chromatography.
    Immunogen
    14 amino acid peptide sequence near the carboxy terminus of Human IRF7.
    Isotype
    IgG
  • Application Notes
    Western Blot: 1.0-2.0 μg/mL. This antibody detects a band of approximately 51 kDa in 293 whole cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    IRF7
    Alternative Name
    IRF7 (IRF7 Antibody Abstract)
    Synonyms
    wu:fl24c03, zgc:66043, zgc:77947, IRF7, irf7, IRF-7H, IRF7A, IRF7B, IRF7C, IRF7H, interferon regulatory factor 7, irf7, IRF7, Irf7
    Background
    IRF7 is a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production. Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.Synonyms: IRF-7, Interferon regulatory factor 7
    Gene ID
    3665
    NCBI Accession
    NP_001563
    UniProt
    Q92985
    Pathways
    TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
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