DACT3
Reactivity: Human
IF (cc), IF (p)
Host: Rabbit
Polyclonal
Alexa Fluor 555
Application Notes
ELISA. Western blot (1: 250 - 500) . Immunohistochemistry on Paraffin embedded tissues (1: 50). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
1.0 mg/mL
Buffer
PBS, pH 7.4, containing 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date
12 months
Target
DACT3
(Dapper, Antagonist of beta-Catenin, Homolog 3 (DACT3))
DACT3, a member of the DACT (Dpr/Frodo) gene family, plays an important role in a negative regulator of Wnt/-catenin signaling. Unlike other Wnt signaling inhibitors that are silenced by DNA methylation, DACT3 repression is associated with bivalent histone modifications.Synonyms: DAPPER3, RRR1, antagonist of beta-catenin dapper homolog 3, arginine-rich region 1 protein, dapper homolog 3