ERN1 antibody (AA 699-711)

Catalog No. ABIN343041

Product Details anti-ERN1 Antibody

Target: ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

Binding Specificity: AA 699-711

Reactivity: Human, Monkey, Rabbit

Host: Goat

Clonality: Polyclonal

Conjugate: This ERN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human ERN1 / IRE1.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Rabbit, Opossum (100%) Mouse, Rat, Elephant, Panda, Bovine, Dog, Bat, Horse, Pig, Turkey, Chicken, Platypus (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-PNAHGKIKAMISD from an internal region of human ERN1 / IRE1 (NP_001424.3). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Rabbit, Opossum (100%), Mouse, Rat, Elephant, Panda, Bovine, Dog, Bat, Horse, Pig, Turkey, Chicken, Platypus (92%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:8000, 0.03 - 0.1 μg/mL), WB (0.03 - 0.1 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:8000. Western Blot: Approx. 110kD band observed in Human Pancreas lysates (calculated MW of 110kD according to NP_001424.3). Recommended concentration: 0.03-0.1 μg/mL.

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for ERN1

Target: ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

Alternative Name: ERN1 / IRE1 (ERN1 Products)

Synonyms: IRE1 antibody, IRE1P antibody, IRE1a antibody, hIRE1p antibody, 9030414B18Rik antibody, AI225830 antibody, C85377 antibody, Ire1a antibody, Ire1alpha antibody, Ire1p antibody, RGD1559716 antibody, Ern1 antibody, Ire1 antibody, Ire1b antibody, sb:eu1005 antibody, zgc:109932 antibody, endoplasmic reticulum to nucleus signaling 1 antibody, endoplasmic reticulum to nucleus signaling 2 antibody, endoplasmic reticulum (ER) to nucleus signalling 1 antibody, serine/threonine-protein kinase/endoribonuclease IRE1 antibody, endoplasmic reticulum (ER) to nucleus signalling 2 antibody, ERN1 antibody, ERN2 antibody, Ern1 antibody, LOC524719 antibody, Ern2 antibody, ern1 antibody

Background: Name/Gene ID: ERN1
Subfamily: IRE
Family: Protein Kinase

Synonyms: ERN1, ER to nucleus signalling 1, Inositol-requiring enzyme 1, Inositol-requiring protein 1, Ire1-alpha, IRE1a, HIRE1p, IRE1, Inositol-requiring 1, IRE1P

Gene ID: 2081

NCBI Accession: NP_001424

UniProt: O75460

Pathways: ER-Nucleus Signaling, Unfolded Protein Response