MBP antibody

Catalog No. ABIN356475

Product Details anti-MBP Antibody

Target: MBP (Myelin Basic Protein (MBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBP antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody stains white matter and oligodendrocyte.
Cellular Localization: Cytoplasmic.

Purification: Purified

Immunogen: Purified human MBP.

Isotype: IgG

Application Details

Application Notes: Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears): 1/50-1/100 usingstreptavidinapprox. biotin system or polymer system. Immunofluorescence. Recommended positive control: Human brain.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 2.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.05 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for MBP

Target: MBP (Myelin Basic Protein (MBP))

Alternative Name: Myelin Basic Protein (MBP Products)

Synonyms: C76307 antibody, Hmbpr antibody, R75289 antibody, golli-mbp antibody, mld antibody, shi antibody, Mbps antibody, cb274 antibody, fj33b11 antibody, mbp antibody, wu:fj33b11 antibody, wu:fq15b02 antibody, zgc:136630 antibody, MGC115135 antibody, myelin basic protein antibody, myelin basic protein a antibody, myelin basic protein L homeolog antibody, MBP antibody, Mbp antibody, mbpa antibody, mbp antibody, mbp.L antibody

Background: Myelin Basic Protein (MBP) a 19.6 kDa highly basic protein is a major constituent of central nervous system (CNS). This protein is synthesized by oligodendrocyte and Schwann cells. MBP, Proteolipid (PLP), myelin oligodendrocyte glycoprotein (MOG) are primary encephaltogenic target antigens in multiple sclerosis. The gene for MBP is on chromosome 18, the protein localizes to CNS and to various cells of the hematopoietic system. MBP is expressed in oligodendrocyte, myelin of white matter, spinal cord and in peripheral nervesSynonyms: MBP, Myelin membrane encephalitogenic protein

Gene ID: 4155

NCBI Accession: NP_001020252

UniProt: P02686