FOXO3 antibody (AA 251-255)
Quick Overview for FOXO3 antibody (AA 251-255) (ABIN362792)
Target
See all FOXO3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 251-255
-
Specificity
- The antibody detects endogenous level of total FKHRL1 protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
-
Immunogen
- Peptide sequence around AA 251-255 (A-V-S-M-D) derived from Human FKHRL1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
-
Isotype
- IgG
-
-
-
-
Application Notes
- Western blotting: 1:500-1:1000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C/-20 °C
-
Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
-
- FOXO3 (Forkhead Box O3 (FOXO3))
-
Alternative Name
- FKHRL1
-
Background
- Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.
-
Molecular Weight
- 97 kDa
-
NCBI Accession
- NP_001446
-
UniProt
- O43524
-
Pathways
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
Target
-