ICAM1 antibody (Biotin)
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- Target See all ICAM1 Antibodies
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ICAM1 antibody is conjugated to Biotin
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Application
- Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- The antigen is CD54, the antibody recognizes an epitope on domain 1 of the molecule as tested on transfectants. Biochemistry: Clone 1304 stains a 95kD single chain integral membrane glycoprotein. The epitope is stable against acetone or paraformaldehyde fixation. ICAM-1 also functions as a rhinovirus receptor. Antigen distribution: Isolated cells: ICAM-1 expression can be induced on endothelial cells by in vitro stimulation with IL-1, TNF-alpha and IFN-gamma. Tissue sections: In inflamed lesions, the antibody reacts with stimulated endothelial cells, epithelial cells and fibroblasts and with haemopoietic cells such as macrophages, dendritic cells in Peyer's patches, lymph nodes and tonsils. Specificity: Human: CD54. Other: not tested.
- Purification
- Affinity purified
- Immunogen
- cultured human endothelial cells
- Clone
- 1304
- Top Product
- Discover our top product ICAM1 Primary Antibody
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- Application Notes
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Approved: IHC, IHC-P (1:800)
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- 0.5 mL distilled water
- Concentration
- Lot specific
- Buffer
- Lyophilized from PBS pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 4°C.
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- Target
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- Alternative Name
- ICAM1 / CD54 (ICAM1 Products)
- Synonyms
- BB2 antibody, CD54 antibody, P3.58 antibody, Icam-1 antibody, Ly-47 antibody, MALA-2 antibody, ICAM antibody, ICAM-1 antibody, ICAM1 antibody, intercellular adhesion molecule 1 antibody, intercellular adhesion molecule-1 antibody, ICAM1 antibody, Icam1 antibody, ICAM-1 antibody
- Target Type
- Viral Protein
- Background
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Name/Gene ID: ICAM1
Family: ICAM
Synonyms: ICAM1, BB2, CD54 antigen, CD54, ICAM-1, p3.58 - Gene ID
- 3383
- UniProt
- P05362
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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