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ITGA2 antibody
ITGA2
Reactivity: Human
IHC, IHC (fro)
Host: Mouse
Monoclonal
A-1-43
unconjugated
Product Details anti-ITGA2 Antibody
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Target
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ITGA2
(Integrin alpha 2 (ITGA2))
Reactivity
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Human
Host
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Mouse
Clonality
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Monoclonal
Conjugate
All conjugates for ITGA2 antibodies
This ITGA2 antibody is un-conjugated
Application
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Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
Specificity
The antigen is CD49b, the epitope has not been further characterized. Antigen distribution: Isolated cells: The antibody is positive on the following melanoma cell lines: BRO, SK-Mel-13, SK-Mel-19, SK-Mel-29, SK-Mel-113, and negative on normal monocytes. Tissue sections: Acetone fixed tissue sections of melanoma larger than 1.5mm show positive staining whereas the majority of benign melanocytic nevi (>95 % ) are negative. Specificity: Human: CD49b. Other: not tested.
Purification
Affinity purified
Immunogen
Type of Immunogen: Native protein
Clone
A-1-43
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Alternatives
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Application Details
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Application Notes
Approved: IHC, IHC-Fr (1:100 - 1:800)
Restrictions
For Research Use only
Handling
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Format
Lyophilized
Reconstitution
0.5 mL distilled water
Concentration
Lot specific
Buffer
Lyophilized from PBS pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store at 4°C.
Target Details for ITGA2
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Target
ITGA2
(Integrin alpha 2 (ITGA2))
Alternative Name
ITGA2 / CD49b (ITGA2 Products )
Synonyms
BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody
Background
Name/Gene ID: ITGA2 Family: Integrin Synonyms: ITGA2, Alpha2 integrin, BR, CD49b antigen, CD49B, Integrin alpha2, Integrin Alpha 2, Integrin alpha-2, HPA-5, VLA-2, VLAA2, VLA-2 subunit alpha, Collagen receptor, GPIa, Platelet antigen Br, Platelet glycoprotein GPIa, VLA2 receptor, alpha-2 subunit
Gene ID
3673
UniProt
P17301
Pathways
CXCR4-mediated Signaling Events , Smooth Muscle Cell Migration , Integrin Complex
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