This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This LEO1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S10 of human LEO1.
LEO1 antibody, RDL antibody, Gm185 antibody, zgc:77374 antibody, LEO1 homolog, Paf1/RNA polymerase II complex component antibody, Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) antibody, RNA polymerase-associated protein LEO1 antibody, LEO1 homolog, Paf1/RNA polymerase II complex component S homeolog antibody, Leo1, Paf1/RNA polymerase II complex component antibody, LEO1 antibody, leo1 antibody, LOC100466503 antibody, leo1.S antibody, Leo1 antibody, LOC415420 antibody, LOC478310 antibody
Background
The PAF1 complex is a multifunctional complex. The PAF1 complex interacts with POLR2A. May be involved in both initiation and elongation, histone methylation and RNA processing. Overexpression of LEO1 induces cell growth arrest and premature senescence of fibroblasts.