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Leptin Receptor antibody (LEPR) (AA 23-52) Primary Antibody

LEPR Reactivity: Human FACS, IHC (p), WB Host: Rabbit Polyclonal RB02053 unconjugated
Catalog No. ABIN390093
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  • Target See all Leptin Receptor (LEPR) Antibodies
    Leptin Receptor (LEPR)
    Binding Specificity
    • 17
    • 16
    • 14
    • 10
    • 10
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-52, N-Term
    Reactivity
    • 123
    • 76
    • 48
    • 16
    • 2
    • 1
    Human
    Host
    • 111
    • 16
    • 9
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 118
    • 21
    Polyclonal
    Conjugate
    • 57
    • 12
    • 9
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    This Leptin Receptor antibody is un-conjugated
    Application
    • 73
    • 70
    • 34
    • 27
    • 25
    • 16
    • 14
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This Leptin Receptor (LEPR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human Leptin Receptor (LEPR).
    Clone
    RB02053
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Leptin Receptor (LEPR)
    Abstract
    LEPR Products
    Synonyms
    CD295, LEP-R, LEPRD, OB-R, OBR, obr, cd295, ob-rb, Fa, LEPROT, Leprb, Modb1, OB-RGRP, Obr, db, diabetes, obese-like, obl, ObRb, Ob-R, Ob-RM, lepr, leptin receptor, leptin receptor S homeolog, LEPR, lepr, Lepr, lepr.S
    Background
    Leptin, an adipocyte-specific hormone, regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure by acting through the leptin receptor (LEPR). LEPR is a single-transmembrane-domain receptor of the cytokine receptor family that is identical to the mouse diabetes (db) gene product. During weight loss, leptin levels decrease, whereas soluble LEPR levels and the receptor bound fraction of leptin increases. The presence of LEPR in the absorptive cells of the small intestine suggests that leptin may have a physiological role in the regulation of nutrient absorption.
    Molecular Weight
    132494
    Gene ID
    3953
    NCBI Accession
    NP_001003679, NP_001003680, NP_001185616, NP_001185617, NP_001185618, NP_002294
    UniProt
    P48357
    Pathways
    JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour
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