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Prohibitin 2 antibody (AA 106-134)

PHB2 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB15314 unconjugated
Catalog No. ABIN391412
  • Target See all Prohibitin 2 (PHB2) Antibodies
    Prohibitin 2 (PHB2)
    Binding Specificity
    • 16
    • 8
    • 8
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 106-134
    Reactivity
    • 75
    • 39
    • 15
    • 11
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 73
    • 2
    • 2
    Rabbit
    Clonality
    • 74
    • 3
    Polyclonal
    Conjugate
    • 47
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Prohibitin 2 antibody is un-conjugated
    Application
    • 66
    • 25
    • 22
    • 18
    • 16
    • 13
    • 13
    • 10
    • 10
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    B, C, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PHB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from human PHB2.
    Clone
    RB15314
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PHB2 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Prohibitin 2 (PHB2)
    Alternative Name
    PHB2 (PHB2 Products)
    Synonyms
    bcap37 antibody, zgc:73150 antibody, wu:fc28c08 antibody, PHB2 antibody, phb2 antibody, ATPHB2 antibody, F21M11.21 antibody, F21M11_21 antibody, prohibitin 2 antibody, DKFZp469N1310 antibody, BAP antibody, BCAP37 antibody, Bap37 antibody, PNAS-141 antibody, REA antibody, p22 antibody, bap37 antibody, prohibitin2 antibody, xphb2 antibody, AU044498 antibody, Bcap37 antibody, Bap antibody, Bap-37 antibody, Bcap27 antibody, prohibitin 2a antibody, prohibitin 2 antibody, prohibitin 2 S homeolog antibody, phb2a antibody, PHB2 antibody, phb2 antibody, phb2.S antibody, Phb2 antibody
    Background
    PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity and is probably involved in regulating mitochondrial respiration activity and in aging.
    Molecular Weight
    33296
    Gene ID
    11331
    NCBI Accession
    NP_001138303, NP_001254629
    UniProt
    Q99623
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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