ENPP3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB24586
unconjugated
Application Notes
Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 mLof whole bloodor 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. Immunoflourescence. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
PBS, 15 mM Sodium Azide, 0.2 % high-grade protease free BSA as a stabilizing agent
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store at 2-8 °C. Do not freeze. This antibody is photosensitive and should be protected fromlight. Shelf life: One year from despatch.
CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.Synonyms: E-NPP 3, Ectonucleotide pyrophosphatase / phosphodiesterase family member 3, PD-I beta, PDNP3, Phosphodiesterase I beta, Phosphodiesterase I/nucleotide pyrophosphatase 3