MUC16 antibody

Catalog No. ABIN452566

Product Details anti-MUC16 Antibody

Target: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC16 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Specificity: Reactive with Human CA125.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: MUC16, MUC-16, CA-125, CA 125, Ovarian carcinoma antigen CA125, Ovarian cancer-relatedtumor marker CA125

Purification: Affinity Chromatography on Protein G.

Immunogen: Human CA125.

Clone: 7

Isotype: IgG2a

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2 without preservatives.

Preservative: Without preservative

Storage: -20 °C

Storage Comment: Store the antibody at -20 °C. After reconstitution, aliquot and store at -20 °C.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for MUC16

Target: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Alternative Name: Mucin-16 / CA125 (CA125 Products)

Synonyms: CA125 antibody, 1110008I14Rik antibody, Ca125 antibody, Gm1480 antibody, RGD1308422 antibody, MUC16 antibody, mucin 16, cell surface associated antibody, mucin 16 antibody, mucin-16 antibody, MUC16 antibody, Muc16 antibody, LOC476718 antibody, LOC712735 antibody

Background: Mucin16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller subunits being described by some investigators.Synonyms: CA 125, CA-125, MUC-16, MUC16, Ovarian cancer-related tumor marker CA125, Ovarian carcinoma antigen CA125

Gene ID: 94025

UniProt: Q8WXI7