PNPLA6 antibody (AA 496-510)

Catalog No. ABIN466820

Product Details anti-PNPLA6 Antibody

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Binding Specificity: AA 496-510

Reactivity: Human, Cow, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This PNPLA6 antibody is un-conjugated

Application: ELISA

Specificity: Human PNPLA6.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Bovine, Pig (100%) Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Dog, Bat, Rabbit (93%) Elephant, Horse, Opossum, Chicken, Lizard (87%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-YQGRQTSSIFEAAKQ from an internal region of human PNPLA6 (NP_006693.3). Percent identity by BLAST analysis: Human, Gorilla, Bovine, Pig (100%), Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Dog, Bat, Rabbit (93%), Elephant, Horse, Opossum, Chicken, Lizard (87%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA

Usage: Western Blot: Preliminary experiments gave an approx 75kD band in lysates of cell lines HeLa and Kelly after 2 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 146kD according to NP_006693.3. The 75kD band was successfully blocked by incubation with the immunizing peptide. Have any further splice variants/modified forms been reported?

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for PNPLA6

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Alternative Name: PNPLA6 (PNPLA6 Products)

Synonyms: NTE antibody, NTEMND antibody, SPG39 antibody, iPLA2delta antibody, sws antibody, AI661849 antibody, MSws antibody, Nte antibody, RGD1564611 antibody, wu:fy20f06 antibody, patatin like phospholipase domain containing 6 antibody, patatin-like phospholipase domain containing 6 antibody, PNPLA6 antibody, Pnpla6 antibody, pnpla6 antibody

Background: Name/Gene ID: PNPLA6

Synonyms: PNPLA6, IPLA2delta, Sws, Neuropathy target esterase, NTEMND, SPG39, NTE

Gene ID: 10908

NCBI Accession: NP_006693

UniProt: Q8IY17

Pathways: Ribonucleoside Biosynthetic Process