HTR7 antibody (AA 433-445)

Catalog No. ABIN477934

Product Details anti-HTR7 Antibody

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Binding Specificity: AA 433-445

Reactivity: Human, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This HTR7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human HTR7 / 5-HT7. This antibody is expected to recognize isoform a (NP_000863.1) only.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gibbon, Monkey (100%) Guinea pig (92%) Dog, Opossum (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide QNADYCRKKGHDS from the C-terminus of human HTR7 / 5-HT7 (NP_000863.1). Percent identity by BLAST analysis: Human, Gibbon, Monkey (100%), Guinea pig (92%), Dog, Opossum (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA, WB (1 - 3 μg/mL)

Usage: Western Blot: Approx 50kD band observed in lysates of cell line KELLY (calculated MW of 49.5kD according to NP_000863.1). Recommended concentration: 1-3 μg/mL. An additional band of unknown identity was also consistently observed at 37kD. This band was successfully blocked by incubation with the immunizing peptide.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for HTR7

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Alternative Name: HTR7 / 5-HT7 Receptor (HTR7 Products)

Synonyms: 5-HT7 antibody, 5-HT-dro antibody, 5-HT-dro1 antibody, 5-HT7Dro antibody, 5-HT[7]Dro antibody, 5-HT[[7Dro]] antibody, 5-HT[[7]] antibody, 5-HT[[7]]Dro antibody, 5-HT[[dro1]] antibody, 5-HTdro1 antibody, 5HT-7 antibody, 5HT-R1 antibody, 5HT-dro antibody, 5HT-dro1 antibody, 5HT[[7Dro]] antibody, 5htdror antibody, CG12073 antibody, DRO1 antibody, Dm5HTdro1 antibody, Dmel\\CG12073 antibody, 5Ht7 antibody, 5HT7 antibody, htr7-A antibody, 5-hydroxytryptamine receptor 7 antibody, 5-hydroxytryptamine (serotonin) receptor 7 antibody, 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled antibody, 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled L homeolog antibody, HTR7 antibody, 5-HT7 antibody, LOC752003 antibody, Htr7 antibody, htr7.L antibody

Background: Name/Gene ID: HTR7
Subfamily: Serotonin
Family: GPCR

Synonyms: HTR7, 5-HT7, 5-HT7 receptor, 5-HT-7, 5-hydroxytryptamine 7 receptor, 5HT7, 5-HT-X, 5-hydroxytryptamine receptor 7, 5HT7 Receptor, HT7, Serotonin 5-HT7 receptor, Serotonin receptor 7

Gene ID: 3363

NCBI Accession: NP_000863

UniProt: P34969

Pathways: JAK-STAT Signaling