PPP2R1B antibody (AA 7-19)

Catalog No. ABIN479957

Product Details anti-PPP2R1B Antibody

Target: PPP2R1B (Protein Phosphatase 2, Regulatory Subunit A, beta (PPP2R1B))

Binding Specificity: AA 7-19

Reactivity: Human, Mouse, Rat, Monkey, Pig, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Dog, Xenopus laevis, Insect, Drosophila melanogaster, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R1B antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Specificity: Recognizes human PP 2A/A (65kD). Species cross-reactivity: mouse, rat and bovine. Does not cross-react with other protein phosphatase isoforms.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Elephant, Panda, Horse, Rabbit, Pig, Opossum, Platypus, Xenopus, Salmon, Zebrafish, Stickleback, Seq squirt, Drosophila, Water flea, Mosquito, Ant, Nematode, Beetle, Capsaspora (100%).

Purification: Affinity purified

Immunogen: PP 2A/A peptide aa 7-19, DDSLYPIAVLIDE, conjugated to KLH. Peptide corresponds to the N-terminal peptide of PP 2A/A regulatory subunit having a MW of 65kD. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Elephant, Panda, Horse, Rabbit, Pig, Opossum, Platypus, Xenopus, Salmon, Zebrafish, Stickleback, Seq squirt, Drosophila, Water flea, Mosquito, Ant, Nematode, Beetle, Capsaspora (100%).

Isotype: IgG

Application Details

Application Notes: Approved: ICC (10 - 15 μg/mL), IP, WB (5 - 10 μg/mL)

Usage: Suitable for use in Western Blot, Immunocytochemistry, and Immunoprecipitation. Western Blot: 5-10 μg/mL. Immunocytochemistry: 10-15 μg/mL. Immunoprecipitation: Can be used in conjunction with anti-PP2A/C to immunoprecipitate heterotrimeric PP2A. Optimum dilutions to be determined by researcher.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.08 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Target Details for PPP2R1B

Target: PPP2R1B (Protein Phosphatase 2, Regulatory Subunit A, beta (PPP2R1B))

Alternative Name: PPP2R1B (PPP2R1B Products)

Synonyms: 2410091N08Rik antibody, AI790395 antibody, PP2A-Abeta antibody, PR65B antibody, protein phosphatase 2, regulatory subunit A, beta antibody, protein phosphatase 2 scaffold subunit Abeta antibody, protein phosphatase 2 scaffold subunit A beta antibody, protein phosphatase 2 regulatory subunit A, beta S homeolog antibody, Ppp2r1b antibody, PPP2R1B antibody, ppp2r1b.S antibody

Background: Name/Gene ID: PPP2R1B

Synonyms: PPP2R1B, PR65B, PP2A subunit A isoform R1-beta, PP2A-Abeta

Gene ID: 5519

UniProt: P30154

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades