HVEM antibody (AA 39-202)

Catalog No. ABIN4886749

Product Details anti-HVEM Antibody

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Binding Specificity: AA 39-202

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HVEM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 14(TNFRSF14) detection. Tested with WB, ELISA in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 14(TNFRSF14) detection. Tested with WB, ELISA in Human.
Gene Name: TNF receptor superfamily member 14
Protein Name: Tumor necrosis factor receptor superfamily member 14

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human TNFRSF14/HVEM recombinant protein (Position: L39-V202).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for HVEM

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Alternative Name: TNFRSF14 (TNFRSF14 Products)

Synonyms: ATAR antibody, CD270 antibody, HVEA antibody, HVEM antibody, LIGHTR antibody, TR2 antibody, Atar antibody, HveA antibody, Hvem antibody, Tnfrs14 antibody, TNF receptor superfamily member 14 antibody, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) antibody, Tnfrsf14 antibody, TNFRSF14 antibody

Target Type: Viral Protein

Background: Herpesvirus entry mediator (HVEM), also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of the TNF-receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants.

Synonyms: HVEML | ATAR | CD270 | HveA | HVEM | HVEM L | LIGHT | LIGHTR | TNFRSF14 | TNFSF 14 | TR2 | Q92956

Gene ID: 8764

UniProt: Q92956

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints