WWP1 antibody (WW Domain Containing E3 Ubiquitin Protein Ligase 1) (Internal Region)

Details for Product anti-WWP1 Antibody No. ABIN4889365, Supplier: Log in to see
Antigen
  • AIP5
  • Tiul1
  • hSDRP1
  • 8030445B08Rik
  • SDRP1
  • WWP1
  • aip5
  • tiul1
  • hsdrp1
  • WW domain containing E3 ubiquitin protein ligase 1
  • WWP1
  • Wwp1
  • wwp1
Epitope
Internal Region
4
3
3
2
2
2
Reactivity
Human
29
8
7
2
2
2
2
1
1
1
Host
Rabbit
21
8
Clonality
Polyclonal
Application
ELISA, Western Blotting (WB)
25
15
9
6
5
3
1
1
Options
Supplier
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Immunogen Synthetic peptide derived from internal part of human WWP1 protein
Specificity Reacts with human WWP1 protein
Purification Purified (protein A)
Plasmids, Primers & others Plasmids, Primers & others WWP1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name NEDD4-Like E3 Ubiquitin-Protein Ligase WWP1 (WWP1 Antibody Abstract)
Background E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1, the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF
UniProt Q9H0M0
Application Notes

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only :
WB(1:200 - 1:2000)

Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Concentration 1 mg/mL
Buffer Tris 0,1M, glycine 0,1M, sucrose 2 %
Storage 4 °C/-20 °C
Storage Comment Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
Expiry Date 24 months
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