RHOH (C-Term) antibody

Details for Product No. ABIN4889497, Supplier: Log in to see
Antigen
  • ARHH
  • TTF
  • 5830400A04Rik
  • AU019774
  • Arhh
  • ras homolog family member H
  • RHOH
  • Rhoh
Epitope
C-Term
18
17
6
4
2
2
1
1
Reactivity
Human
60
21
21
3
Host
Rabbit
54
6
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
Application
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
51
40
21
15
7
4
3
1
Options
Supplier
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Immunogen Synthetic peptide derived from C terminal domain of human RhoH
Specificity Reacts with human RhoH protein
Purification Purified (protein A)
Antigen
Alternative Name rho-Related GTP-Binding Protein RhoH
Background Negative regulator of hematopoietic progenitor cell proliferation, survival and migration. Critical regulator of thymocyte development and T-cell antigen receptor (TCR) signaling by mediating recruitment and activation of ZAP70. Required for phosphorylation of CD3Z, membrane translocation of ZAP70 and subsequent activation of the ZAP70-mediated pathways. Essential for efficient beta-selection and positive selection by promoting the ZAP70-dependent phosphorylation of the LAT signalosome during pre-TCR and TCR signaling. Crucial for thymocyte maturation during DN3 to DN4 transition and during positive selection.
UniProt Q15669
Application Notes

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- IHC : 1/200 to 1/2 000 - WB : 1/500 to 1/5 000

Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Buffer Tris 0,1M, glycine 0,1M, sucrose 2 %
Storage 4 °C/-20 °C
Storage Comment Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
Expiry Date 24 months
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