JAK3 antibody

Catalog No. ABIN4901830

This Mouse Monoclonal antibody specifically detects JAK3 in WB, ELISA, IF and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for JAK3 antibody (ABIN4901830)

Target: JAK3 (Janus Kinase 3 (JAK3))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This JAK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 5H2

Product Details anti-JAK3 Antibody

Purpose: Mouse monoclonal to JAK3.

Specificity: JAK3 Monoclonal Antibody detects endogenous levels of JAK3 protein.

Characteristics: Mouse Monoclonal to JAK3.

Purification: Affinity purification

Immunogen: Purified recombinant fragment of human JAK3 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB 1:500-1:2000
IF 1:200-1:1000
FC 1:200-1:400
ELISA 1:10000

Comment:

In NK cells and an NK-like cell line but not in resting T-cells or in other tissues. The S-form is more commonly seen in hematopoietic lines, whereas the B-form is detected in cells both of hematopoietic and epithelial origins.

Restrictions: For Research Use only

Handling

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for JAK3

Target: JAK3 (Janus Kinase 3 (JAK3))

Alternative Name: JAK3

Gene ID: 3718

UniProt: P52333

Pathways: JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response