EEA1 antibody
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- Target See all EEA1 Antibodies
- EEA1 (Early Endosome Antigen 1 (EEA1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EEA1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- EEA1 is an early endosomal marker and a Rab5 effector protein essential for early endosomal membrane fusion and trafficking (1-2). The carboxy terminus of EEA1 contains a FYVE domain which binds to phosphatidylinositol-3-phosphate (PtdIns(3)P), targeting EEA1 to early endosomes (3). The stable association of EEA1 with the endosomal membrane is regulated by PI3 kinase, Rab5 and calcium/calmodulin (4-6). Once on the membrane, EEA1 interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion (7).1.Mu, F.T. et al. (1995) J. Biol. Chem. 270, 13503-13511.2.Christoforidis, S. et al. (1999) Nature 397, 621-625.3.Gaullier, J.M. et al. (1998) Nature 394, 432-433.4.Patki, V. et al. (1997) Proc. Natl. Acad. Sci. USA 94, 7326-7330.5.Lawe, D.C. et al. (2003) Mol. Biol. Cell 14, 2935-2945.6.Simonsen, A. et al. (1998) Nature 394, 494-498.7.McBride, H.M. et al. (1999) Cell 98, 377-386.
- Purification
- Affinity purification
- Immunogen
- Recombinant Protein of human EEA1.
- Isotype
- IgG
- Top Product
- Discover our top product EEA1 Primary Antibody
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anti-Early Endosome Antigen 1 (EEA1) (AA 1312-1411) antibody
EEA1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1D4 unconjugated
anti-Early Endosome Antigen 1 (EEA1) (AA 1312-1411) antibodyEEA1 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 2G2 unconjugated
anti-Early Endosome Antigen 1 (EEA1) (AA 734-875) antibodyEEA1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Early Endosome Antigen 1 (EEA1) (AA 1312-1411) antibodyEEA1 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Early Endosome Antigen 1 (EEA1) (C-Term) antibodyEEA1 Reactivity: Human, Mouse, Rat, Dog, Hamster, Horse, Rabbit, Cow, Monkey, Pig, Guinea Pig, Chicken, Cat, Donkey, Goat, Sheep, Avian WB, IF Host: Goat Polyclonal unconjugated
anti-Early Endosome Antigen 1 (EEA1) antibodyEEA1 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Early Endosome Antigen 1 (EEA1) (AA 1251-1350) antibodyEEA1 Reactivity: Human, Hamster ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Early Endosome Antigen 1 (EEA1) (N-Term) antibodyEEA1 Reactivity: Human, Rat WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Early Endosome Antigen 1 (EEA1) (AA 2-13) antibodyEEA1 Reactivity: Human, Mouse, Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Early Endosome Antigen 1 (EEA1) (N-Term) antibodyEEA1 Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig WB, IHC, IP Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C.
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- Target
- EEA1 (Early Endosome Antigen 1 (EEA1))
- Alternative Name
- EEA1 (EEA1 Products)
- Synonyms
- MST105 antibody, MSTP105 antibody, ZFYVE2 antibody, im:7151048 antibody, si:ch211-276p10.2 antibody, A430109M19Rik antibody, B230358H09Rik antibody, early endosome antigen 1 antibody, early endosome antigen 1 S homeolog antibody, EEA1 antibody, eea1 antibody, Eea1 antibody, eea1.S antibody
- Gene ID
- 8411
- UniProt
- Q15075
- Pathways
- Toll-Like Receptors Cascades
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