ABCC8 antibody (AA 1559-1571)

Catalog No. ABIN490470

Product Details anti-ABCC8 Antibody

Target: ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))

Binding Specificity: AA 1559-1571

Reactivity: Human, Dog, Cow, Horse

Host: Goat

Clonality: Polyclonal

Conjugate: This ABCC8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human ABCC8 / MRP8.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Elephant, Panda, Bovine, Dog, Horse (100%) Marmoset, Mouse, Rat, Bat, Rabbit, Pig (92%) Hamster (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-EFDKPEKLLSRKD from the C-terminus of human ABCC8 / MRP8 (NP_000343.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Elephant, Panda, Bovine, Dog, Horse (100%), Marmoset, Mouse, Rat, Bat, Rabbit, Pig (92%), Hamster (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:8000), WB (0.5 - 1.5 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Approx 170  kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 177  kDa according to NP_000343.2). Recommended concentration: 0.5-1.5 μg/mL. An additional band of unknown identity was also consistently observed at 23  kDa. This band was successfully blocked by incubation with the immunising peptide.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for ABCC8

Target: ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))

Alternative Name: ABCC8 / SUR1 (ABCC8 Products)

Synonyms: ABC36 antibody, HHF1 antibody, HI antibody, HRINS antibody, MRP8 antibody, PHHI antibody, SUR antibody, SUR1 antibody, SUR1delta2 antibody, TNDM2 antibody, D930031B21Rik antibody, Sur antibody, Sur1 antibody, ATP binding cassette subfamily C member 8 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 8 antibody, ABCC8 antibody, Abcc8 antibody

Background: Name/Gene ID: ABCC8
Subfamily: ATP-binding cassette - ABCC/MRP
Family: Transporter

Synonyms: ABCC8, ABC36, HI, PHHI, Sulfonylurea receptor, SUR, Sulfonylurea receptor 1, MRP8, SUR1delta2, HHF1, HRINS, SUR1, TNDM2

Gene ID: 6833

NCBI Accession: NP_000343

UniProt: Q09428

Pathways: Negative Regulation of Hormone Secretion