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CDX2 antibody (AA 150-249)

CDX2 Reactivity: Human IF, IHC (p), FACS Host: Mouse Monoclonal CDX2-1690 unconjugated
Catalog No. ABIN4949546
  • Target See all CDX2 Antibodies
    CDX2 (Caudal Type Homeobox 2 (CDX2))
    Binding Specificity
    • 21
    • 17
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-249
    Reactivity
    • 125
    • 47
    • 42
    • 13
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 85
    • 37
    • 3
    Mouse
    Clonality
    • 79
    • 45
    Monoclonal
    Conjugate
    • 80
    • 9
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDX2 antibody is un-conjugated
    Application
    • 75
    • 66
    • 29
    • 26
    • 19
    • 18
    • 14
    • 14
    • 13
    • 13
    • 10
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    Protein G affinity chromatography
    Immunogen
    Amino acids 150-249 from the human protein were used as the immunogen for this CDX2 antibody.
    Clone
    CDX2-1690
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CDX2 Primary Antibody
  • Application Notes
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CDX2 antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells in 0.1ml,IF: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    Preservative
    Azide free
    Storage
    4 °C,-20 °C
    Storage Comment
    Store the CDX2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target
    CDX2 (Caudal Type Homeobox 2 (CDX2))
    Alternative Name
    CDX2 (CDX2 Products)
    Synonyms
    CDX2 antibody, MGC130987 antibody, cdx3-like antibody, CDX-3 antibody, CDX3 antibody, CDX-2 antibody, Cdx-2 antibody, caudal type homeobox 2 antibody, caudal type homeobox 2 L homeolog antibody, caudal type homeo box 2 antibody, CDX2 antibody, cdx2.L antibody, Cdx2 antibody
    Background
    The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
    Pathways
    Peptide Hormone Metabolism, Stem Cell Maintenance
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