Catalase antibody
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- Target See all Catalase (CAT) Antibodies
- Catalase (CAT)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Catalase antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity
- Immunogen
- Amino acids E344-L527 of the human protein were used as the immunogen for the Catalase antibody.
- Isotype
- IgG
- Top Product
- Discover our top product CAT Primary Antibody
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- Application Notes
- Optimal dilution of the Catalase antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (FFPE): 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Storage
- -20 °C
- Storage Comment
- After reconstitution, the Catalase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- Catalase (CAT)
- Alternative Name
- Catalase (CAT Products)
- Synonyms
- 2210418N07 antibody, Cas-1 antibody, Cas1 antibody, Cs-1 antibody, CS1 antibody, Cat01 antibody, Catl antibody, fb68a12 antibody, wu:fb68a12 antibody, CAT antibody, CATA antibody, CG6871 antibody, CT21282 antibody, CatA antibody, DMCATHPO antibody, DROCATHPO antibody, Dmel\\CG6871 antibody, U00145 antibody, bs36h11.y1 antibody, cat antibody, GB11648 antibody, catalase antibody, Cat antibody, BA0843 antibody, DKFZp469E0232 antibody, catalase antibody, Catalase antibody, catalase, gene 2 antibody, CAT antibody, Cat antibody, cat antibody, cat.2 antibody, LOC769804 antibody, BA_0843 antibody
- Background
- Catalase is a key antioxidant enzyme in the bodies defensing against oxidative stress. It is also a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
- UniProt
- P04040
- Pathways
- Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism
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