CYLD antibody (AA 618-956)

Catalog No. ABIN4950719

Product Details anti-CYLD Antibody

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Binding Specificity: AA 618-956

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYLD antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: Amino acids 618-956 of human CYLD were used as the immunogen for the CYLD antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CYLD antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the CYLD antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for CYLD

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Alternative Name: CYLD (CYLD Products)

Synonyms: BRSS antibody, CDMT antibody, CYLD1 antibody, CYLDI antibody, EAC antibody, MFT antibody, MFT1 antibody, SBS antibody, TEM antibody, USPL2 antibody, 2010013M14Rik antibody, 2900009M21Rik antibody, C130039D01Rik antibody, mKIAA0849 antibody, cyld antibody, LRRGT00003 antibody, Rp1 antibody, Rp1h antibody, CYLD lysine 63 deubiquitinase antibody, cylindromatosis (turban tumor syndrome), a antibody, CYLD antibody, Cyld antibody, cylda antibody

Background: CYLD is localized on the long arm of chromosome 16. This gene encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: Q9NQC7

Pathways: Apoptosis, Activation of Innate immune Response