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c-MYC antibody (AA 40-69)

Name: c-MYC antibody (AA 40-69)
SKU: ABIN3029538
Price: 649.42 USD
Availability: InStock

MYC Reactivity: Human WB, ELISA, FACS Host: Rabbit Polyclonal unconjugated

Western blot analysis of anti-Myc antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MYC gene (2). (c-MYC antibody (AA 40-69))

Anti-Myc antibody flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram). (c-MYC antibody (AA 40-69))

FACS

3 images

Catalog No. ABIN3029538

Datasheet as PDF

Target See all c-MYC (MYC) Antibodies

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
Binding Specificity
59

48

44

41

24

22

17

15

15

13

10

7

7

6

6

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 40-69
Reactivity
358

162

114

15

15

13

13

13

9

9

9

6

6

6

5

4

3

3

2

2

1

1

1

1

1

1

1
Human
Host
276

100

7

5

3

1

1
Rabbit
Compatible Secondaries
Clonality
271

121
Polyclonal
Conjugate
191

31

24

23

8

8

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

3

2

2

2

2

2

2

2

1

1

1

1

1

1
This c-MYC antibody is un-conjugated
Application
286

139

97

81

75

57

55

28

26

24

17

14

12

11

7

4

2

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Cross-Reactivity (Details)

Expected species reactivity: Mouse, Rat, Bovine, Pig

Purification

Antigen affinity purified

Immunogen

A portion of amino acids 40-69 from the human protein was used as the immunogen for this anti-Myc antibody.

Isotype

Ig Fraction

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MYC Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

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MYC Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated

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KO Validated MYC Reactivity: Human WB, IF, ChIP Host: Rabbit Monoclonal unconjugated

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MYC Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) antibody
MYC Reactivity: Human ELISA Host: Mouse Monoclonal 7E10 unconjugated

Application Notes

Titration of the anti-Myc antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions

For Research Use only
Format

Liquid

Buffer

In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Aliquot the anti-Myc antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Alternative Name

Myc Proto-Oncogene protein (MYC Products)

Background

MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.

UniProt

P01106

Pathways

p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect