FOXO3 antibody (AA 224-253)
Quick Overview for FOXO3 antibody (AA 224-253) (ABIN3030991)
Target
See all FOXO3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 224-253
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Cross-Reactivity (Details)
- Expected species reactivity: Mouse
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 224-253 from the human protein was used as the immunogen for this FOXO3 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the FOXO3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the FOXO3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Alternative Name
- FOXO3
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Background
- This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
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UniProt
- O43524
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Pathways
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
Target
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