VEGFR2/CD309 antibody (AA 1153-1182)

Catalog No. ABIN3031548

The Rabbit Polyclonal anti-VEGFR2/CD309 antibody (ABIN3031548) specifically detects VEGFR2/CD309 in WB, ELISA and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for VEGFR2/CD309 antibody (AA 1153-1182) (ABIN3031548)

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFR2/CD309 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-VEGFR2/CD309 Antibody

Binding Specificity: AA 1153-1182

Purpose: KDR Antibody / Kinase Insert Domain Receptor / VEGFR2

Purification: Antigen affinity

Immunogen: A portion of amino acids 1153-1182 from the human protein was used as the immunogen for this KDR antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the KDR antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the KDR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for VEGFR2/CD309

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Alternative Name: KDR

Background: KDR is a major growth factor for endothelial cells. This protein encodes one of the two receptors of the KDR. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc..

UniProt: P35968

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling