PDK4 antibody

Catalog No. ABIN3028962

The Mouse Monoclonal anti-PDK4 antibody (Clone 345CT19-6-2) (ABIN3028962) specifically detects PDK4 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for PDK4 antibody (ABIN3028962)

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 345CT19-6-2

Product Details anti-PDK4 Antibody

Purpose: PDK4 Antibody

Purification: Purified

Immunogen: A purified His-tagged recombinant protein fragment was used to produced this monoclonal PDK4 antibody.

Isotype: IgG1

Application Details

Application Notes: Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the PDK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PDK4

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Alternative Name: PDK4

Background: This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

UniProt: Q16654

Pathways: PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect