PDK4 antibody (AA 82-110)

Catalog No. ABIN3028960

This Rabbit Polyclonal antibody specifically detects PDK4 in WB and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for PDK4 antibody (AA 82-110) (ABIN3028960)

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PDK4 Antibody

Binding Specificity: AA 82-110

Cross-Reactivity (Details): Expected species reactivity: Rat

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 82-110 from the mouse protein was used as the immunogen for this Pdk4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Pdk4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Pdk4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PDK4

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Alternative Name: Pdk4

Background: Pdk4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism (By similarity).

UniProt: O70571

Pathways: PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect