PDK4 antibody (AA 1-411)

Catalog No. ABIN562163

There are 3+ publications for this product available. The Mouse Polyclonal anti-PDK4 antibody is suitable to detect PDK4 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for PDK4 antibody (AA 1-411) (ABIN562163)

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This PDK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PDK4 Antibody

Binding Specificity: AA 1-411

Purpose: Mouse polyclonal antibody raised against a full-length recombinant PDK4.

Sequence: MKAARFVLRS AGSLNGAGLV PREVEHFSRY SPSPLSMKQL LDFGSENACE RTSFAFLRQE LPVRLANILK EIDILPTQLV NTSSVQLVKS WYIQSLMDLV EFHEKSPDDQ KALSDFVDTL IKVRNRHHNV VPTMAQGIIE YKDACTVDPV TNQNLQYFLD RFYMNRISTR MLMNQHILIF SDSQTGNPSH IGSIDPNCDV VAVVQDAFEC SRMLCDQYYL SSPELKLTQV NGKFPDQPIH IVYVPSHLHH MLFELFKNAM RATVEHQENQ PSLTPIEVIV VLGKEDLTIK ISDRGGGVPL RIIDRLFSYT YSTAPTPVMD NSRNAPLAGF GYGLPISRLY AKYFQGDLNL YSLSGYGTDA IIYLKALSSE SIEKLPVFNK SAFKHYQMSS EADDWCIPSR EPKNLAKEVA M

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PDK4 (AAH40239.1, 1 a.a. ~ 411 a.a) full-length recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PDK4 antibody (ABIN562163)

Kase, Nikoli?, Bakke, Bogen, Aas, Thoresen, Rustan: "Remodeling of oxidative energy metabolism by galactose improves glucose handling and metabolic switching in human skeletal muscle cells." in: PLoS ONE, Vol. 8, Issue 4, pp. e59972, (2013) (PubMed).

Stenson, Rydén, Steffensen, Wåhlén, Pettersson, Jocken, Arner, Laurencikiene: "Activation of liver X receptor regulates substrate oxidation in white adipocytes." in: Endocrinology, Vol. 150, Issue 9, pp. 4104-13, (2009) (PubMed).

Ribet, Montastier, Valle, Bezaire, Mazzucotelli, Mairal, Viguerie, Langin: "Peroxisome proliferator-activated receptor-alpha control of lipid and glucose metabolism in human white adipocytes." in: Endocrinology, Vol. 151, Issue 1, pp. 123-33, (2009) (PubMed).

Target Details for PDK4

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Alternative Name: PDK4

Background: Full Gene Name: pyruvate dehydrogenase kinase, isozyme 4
Synonyms: FLJ40832

Gene ID: 5166

Pathways: PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect