Calprotectin antibody

Catalog No. ABIN4956353

Product Details anti-Calprotectin Antibody

Target: Calprotectin (S100A8/A9)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calprotectin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Cross-Reactivity: Human

Purification: purified

Immunogen: human recombinant protein

Clone: 69-6-1

Isotype: IgG2b

Application Details

Application Notes: Dilution: WB 1:1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 1 mL deionized water

Buffer: PBS, pH 7.23

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Target Details for Calprotectin

Target: Calprotectin (S100A8/A9)

Alternative Name: calprotectin- S100A8/A9 complex (S100A8/A9 Products)

Synonyms: 60B8AG antibody, CAGB antibody, CFAG antibody, CGLB antibody, L1AG antibody, LIAG antibody, MAC387 antibody, MIF antibody, MRP14 antibody, NIF antibody, P14 antibody, Mrp14 antibody, MRP-14 antibody, p14 antibody, 60B8Ag antibody, AW546964 antibody, BEE22 antibody, Cagb antibody, GAGB antibody, L1Ag antibody, S100 calcium binding protein A9 antibody, S100 calcium binding protein A9 (calgranulin B) antibody, S100A9 antibody, S100a9 antibody

Background: Calprotectin is a functional heterocomplex of small EF hand calcium-binding proteins S100A8 and S100A9. The heterocomplex is expressed in various cells and tissues and induced upon inflammation. The complex is released by neutrophilic granulocytes in inflammatory disorders such as inflammatory bowel disease and rheumatoid arthritis. Released Calprotectin serves as a leukocyte chemoattractant and modulates inflammation via damage receptors. Via it's binding to the receptor of advanced glycation end-products (RAGE), calprotectin is implicated in chronic inflammatory conditions.

Molecular Weight: 45 kDa

Pathways: S100 Proteins